Version: May 1990 Submitted By: W.D. Dupont & W.D. Plummer, Jr, Vanderbilt University School of Medicine Operating System: MS-DOS V3.1, VAX/VMS V4.7 Source Language: FORTRAN 77 Keywords: Mathematical Memory Requirements: 180KB Notes: Executable and/or object code is furnished. This program is described in detail in Dupont & Plummer, "Power and Sample Size Calculations: A Review and Computer Program, Controlled Clinical Trials 1990; 11:116-28". Abstract: The POWER program performs sample size and power
calculations for the most common study designs. This
program can be used for studies with dichotomous, continuous
or survival response measures. The alternative hypotheses
of interest may be specified either in terms of differing
response rates, means, or survival times; or in terms of
relative risks or odds ratios. Studies with dichotomous or
continuous outcomes may be either matched or independent.
The program can determine the sample size needed to detect a
specified alternative hypothesis with the required power,
the power with which a specific alternative hypothesis can
be detected with a given sample size, or the specific
alternative hypotheses that can be detected with a given
power and sample size. This flexibility facilitates an
iterative approach to sample size selection. The program
writes a log file of all calculated estimates and can
produce an output file for plotting power curves.
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